Business Trip
Business Trip explores the frontiers of brain and mental health through conversations with founders, investors, and researchers at the intersection of neuroscience and technology.
Business Trip
Virtual Mitochondrial Models and the Case for Engineering Humans with Mariëlle van Kooten
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Mariëlle van Kooten (CEO and co-founder of Powerhouse Biology) joins to make the case that mitochondria are the best place to start engineering the human body. Her team builds virtual mitochondria models to predict how a fix will behave before it ever touches a patient. Marielle is passionate about treating disease and human enhancement.
In this episode, we discuss:
- Why mitochondria might be the most tractable place to start engineering human biology
- The difference between building a virtual mitochondria model and the industry-wide race to build a virtual cell
- Why a protein fix for one disease (say, Parkinson's-linked muscle weakness) could work across totally unrelated tissues
- The difference between Science vs. Engineering: why she left academia
- The case for human enhancement: longevity, resilience, and why the ethics conversation is stalled
Credits:
Created by Greg Kubin and Matias Serebrinsky
Host: Matias and Greg
Produced by Nico V. Rey
Find us at businesstrip.fm and psymed.ventures
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Theme music by Dorian Love
Additional Music: Distant Daze by Zack Frank